Mr Validity — Diseases -

: When a gene affects multiple traits independently, potentially biasing the causal estimate.

: Occurs if the chosen genetic variant is only weakly linked to the exposure, leading to inaccurate results. Diseases - Mr Validity

: Exposure and outcome are measured in the same group of people. : When a gene affects multiple traits independently,

: Typically single nucleotide polymorphisms (SNPs) identified through Genome-Wide Association Studies (GWAS) . Data Types : Diseases - Mr Validity