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: It is safe for dogs and puppies at least 8 weeks old and weighing 5 pounds or more.

: Your dog must be tested for existing heartworm infections before starting ComboGuard buy comboguard

: Discuss use with your vet if your dog has a history of epilepsy or seizures, as the ingredient spinosad may cause adverse reactions in these pets. Alternatives COMBOGUARD® - Vethical : It is safe for dogs and puppies